Approximately 6500 vertebrates (including 400 type specimens), mainly synapsids that have been collected from the main Karoo Basin over the past 150 years. There are good study collections of Mid-Late Permian taxa including Dinocephalia, Dicynodontia, Gorgonopsia, Therocephalia, Cynodontia and Captorhinida. These include numerous fully prepared near complete skeletons of Pristerognathus, Diictodon, Pareiasaurus , Rhachiocephalus, Galesaurus and Thrinaxodon. More recent acquisitions include a 'nest' of juvenileYoungina, 2 “dwarf” pareiasaur skeletons, a complete skull of the unusual parrot-beaked dicynodont Dinanomodon, and a large collection of bone-bearing therapsid coprolites.
Over 500 accurately-provenenced vertebrate specimens collected from the Permo-Triassic boundary sequence in the Karoo Basin, as part of Roger Smith’s research project, will eventually be accessioned.
A significant collection of Mesozoic dicynodonts, archosauromorphs(including the types of Euparkeria ), dinosaurs (including the types of rare early ornithischians Heterodontosaurus and Eocurser) and numerous mammalian and non-mammalian cynodonts from the Stormberg Group.